GO:0030122 cellular_component AP-2 adaptor complex
| PAG Title | GO:0030122 cellular_component AP-2 adaptor complex |
| PAG ID | TAX020309 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | A heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits, and links clathrin to the membrane surface of a vesicle, and the cargo receptors during receptor/clathrin mediated endocytosis. Vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC). |
| Species | Homo sapiens |
| nCoCo Score | 1,713 |
| Base PAG ID | TAX020309 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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